Specialized Annotation - Antibiotic Resistance
ResFinder 4.1
ResFinder 4.1
(Danish Technical Univcersity) - uses BLAST for identification of
acquired antimicrobial resistance genes in whole-genome data. As input,
the method can use both pre-assembled, complete or partial genomes, and
short sequence reads from four different sequencing platforms. Tested
with 1411 different resistance genes with 100% identity.
(Reference: Zankari E et al. 2012. J Antimicrob
Chemother. 67:2640-2644)
ResFinderFG 2.0
ResFinderFG 2.0 (Danish Technical University) - identifies a resistance phenotype based on a functional metagenomic antibiotic resistance determinants database.
CARD
CARD
(The Comprehensive Antibiotic Resistance Database) - a rigorously curated
collection of known resistance determinants and associated antibiotics,
organized by the Antibiotic Resistance Ontology (ARO) and AMR gene
detection models
(Reference: Jia, B. et al. 2017. Nucleic Acids
Research, 45: D566-573).
BacMet
BacMet
(Antibacterial Biocide & Metal Resistance Genes Database) - a database of
biocide and metal resistance genes with highly reliable content. In
BacMet version 1.1, the experimentally confirmed database contains 704
resistance genes, whereas the predicted database contains 40,556
resistance genes
(Reference: Pal, C. et al. 2014. Nucleic Acids
Research, 42: D737-743).
BacAnt
BacAnt -
which allows the annotation of antimicrobial resistance genes (ARGs), integrons and transposable elements at the same time.
The pipeline generates genbank files automatically, which are compatible with Easyfig for comparative genomic analysis.
(Reference: Hua X et al. 2021. Front Microbiol. 12: 649969).
Updated: February, 2026